Area
Facultad de Ciencias de la Salud
Department
Medicine
Email:
ganeko.bernardo@deusto.esArticles in Scientific Journals
Pseudophosphorylation of single residues of the J-domain of DNAJA2 regulates the holding/folding balance of the Hsc70 system / Protein Science
Velasco Carneros, Lorea; Bernardo Seisdedos, Ganeko; Maréchal, Jean-Didier; Millet Aguilar-Galindo, Oscar; Moro, Fernando; Muga, Arturo
ISBNAR: 0961-8368 / Volume: 33 / Journal number: 8 / Date: 2024
Quantitative Analysis of the Human Semen Phosphorometabolome by 31P-NMR / International Journal of Molecular Sciences
Serrano, Rebeca; Martín Hidalgo, David; Bilbao, Jon; Bernardo Seisdedos, Ganeko; Millet Aguilar-Galindo, Oscar; Garcia Marín, Luis J.; Bragado, María Julia
ISBNAR: 1422-0067 / Volume: 3 / Journal number: 25 / Start page: 1682 / Date: 2024
Redox regulation of KV7 channels through EF3 hand of calmodulin / elife
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2050-084X / Volume: 12 / Date: 2023
Protoporphyrin IX Binds to Iron(II)-Loaded and to Zinc-Loaded Human Frataxin / Life
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2075-1729 / Volume: 13 / Start page: 222 / Date: 2023
ALAD Inhibition by Porphobilinogen Rationalizes the Accumulation of alpha-Aminolevulinate in Acute Porphyrias / Biochemistry
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0006-2960 / Volume: 61 / Start page: 2409 / End page: 2409 / Date: 2022
J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum / Analiytical chemistry
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 1333-1341 / Volume: 94 / Start page: 1333 / End page: 1333 / Date: 2022
Exploration of Human Serum Lipoprotein Supramolecular Phospholipids Using Statistical Heterospectroscopy in n-Dimensions (SHY- n): Identification of Potential Cardiovascular Risk Biomarkers Related to SARS-CoV-2 Infection / Analytical Chemistry
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 4426-4436 / Volume: 94 / Start page: 4426 / End page: 4426 / Date: 2022
Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2 / Journal of Molecular Biology
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0022-2836 / Volume: 434 / Date: 2022
O-GlcNAcylated p53 in the liver modulates hepatic glucose production / Nature Communications
Bernardo Seisdedos, Ganeko
ISBNAR: 2041-1723 / Date: 2021
Metabolic Landscape of the Mouse Liver by Quantitative 31P Nuclear Magnetic Resonance Analysis of the Phosphorome / Hepatology
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0270-9139 / Volume: 74 / Start page: 148 / End page: 148 / Date: 2021
Improving the pharmacological properties of ciclopirox for its use in congenital erythropoietic porphyria / Journal of Personalized Medicine
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2075-4426 / Volume: 11 / Date: 2021
Therapeutic targeting of fumaryl acetoacetate hydrolase in hereditary tyrosinemia type i / International Journal of Molecular Sciences
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 1422-0067 / Volume: 22 / Start page: 1 / End page: 1 / Date: 2021
Identification of novel UROS mutations in a patient with congenital erythropoietic porphyria and efficient treatment by phlebotomy / Molecular Genetics and Metabolism Reports.
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2214-4269 / Volume: 27 / Date: 2021
Conformation-sensitive antibody reveals an altered cytosolic PAS/CNBh assembly during hERG channel gating / Biochemistry
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0006-2960 / Volume: 118 / Date: 2021
Cosolute modulation of protein oligomerization reactions in the homeostatic timescale / Biophysical Journal
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0006-3495 / Volume: 120 / Start page: 2067 / End page: 2067 / Date: 2021
Unravelling the Time Scale of Conformational Plasticity and Allostery in Glycan Recognition by Human Galectin-1 / Chemistry - A European Journal
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0947-6539 / Volume: 26 / Start page: 15643 / End page: 15653 / Date: 2020
An Epoxide Intermediate in Glycosidase Catalysis / American Chemical Society central science
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2374-7943 / Volume: 6 / Journal number: 6 / Start page: 760 / End page: 770 / Date: 2020
Hereditary tyrosinemia type I-associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate / Journal of Biological Chemistry
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0021-9258 / Volume: 294 / Start page: 13051 / End page: 13051 / Date: 2019
Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor / Nature Communications
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2041-1723 / Volume: 10 / Date: 2019
Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria / Science Translational Medicine.
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 1946-6234 / Volume: 10 / Date: 2018
Structural basis of pyrrole polymerization in human porphobilinogen deaminase / Biochimica et Biophysica Acta - General Subjects
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0304-4165 / Volume: 1862 / Start page: 1948 / End page: 1948 / Date: 2018
Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel / Proceedings of the National Academy of Sciences of the United States of America
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0027-8424 / Volume: 115 / Start page: 2395 / End page: 2395 / Date: 2018
From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-a-mannosidase / Organic Letters
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 1523-7060 / Volume: 20 / Start page: 7488 / End page: 7488 / Date: 2018
Missense UROS mutations causing congenital erythropoietic porphyria reduce UROS homeostasis that can be rescued by proteasome inhibition / Human Molecular Genetics
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0964-6906 / Volume: 26 / Start page: 1565 / End page: 1565 / Date: 2017
Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels / Scientific Reports
Bernardo Seisdedos, Ganeko
ISBNAR: 2045-2322 / Volume: 7 / Date: 2017
Disulfide driven folding for a conditionally disordered protein / Scientific Reports
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 2045-2322 / Volume: 7 / Date: 2017
Contribution of shape and charge to the inhibition of a family GH99 endo-a-1,2-mannanase / Journal of the American Chemical Society
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 0002-7863 / Volume: 139 / Start page: 1089 / End page: 1089 / Date: 2017
An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels / Journal of Cell Science
Bernardo Seisdedos, Ganeko
ISBNAR: 0021-9533 / Volume: 128 / Start page: 3155 / End page: 3155 / Date: 2015
Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation / Journal of Cell Science
Bernardo Seisdedos, Ganeko
ISBNAR: 0021-9533 / Volume: 128 / Start page: 4014 / End page: 4014 / Date: 2015
Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex / PLoS ONE
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNAR: 1932-6203 / Volume: 9 / Date: 2014
Articles Published Online
Abnormal concentration of porphyrins in serum from COVID-19 patients
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Date: 2020
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Date: 2000
Chapters of Books
Prospective Metabolomic Studies in Precision Medicine: The AKRIBEA Project / Handbook of Experimental Pharmacology
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Start page: 275 / End page: 275 / Date: 2022
Chapter 3: Receptor-based NMR Techniques in Drug Discovery / RSC Drug Discovery Series
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Start page: 44 / End page: 44 / Date: 2020
Natural and pharmacological chaperones against accelerated protein degradation: uroporphyrinogen III synthase and congenital erythropoietic porphyria / Protein Homeostasis Diseases: Mechanisms and Novel Therapies
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
ISBNCO: 9780128191330 / Start page: 389 / End page: 389 / Date: 2017
Supervised Theses
Estudio de la uroporfirina I como aproximación terapéutica frente a las encefalopatías espongiformes transmisibles.
García Martínez, Sandra
Date: 2020
Optimized Standard Operating Procedures for 31P-NMR Metabolomics on Tissular Extract
Bilbao, Jon; Martín Ramos, Sara; Alarcón Morales, Karen Salua; Diercks, Tammo; Mato De La Paz, José María; Bernardo Seisdedos, Ganeko; Millet Aguilar-Galindo, Oscar
Congress name: Optimized Standard Operating Procedures for 31P-NMR Metabolomics on Tissular Extract / Country: España / Web: https://euromar2024.org/iberoamerican-nmr-satellite-meeting/ / Publication name: Optimized Standard Operating Procedures for 31P-NMR Metabolomics on Tissular Extract / Date: 2024/07/05
Optimized Standard Operating Procedures for 31P-NMR Metabolomics on Tissular Extracts
Bilbao, Jon; Martín Ramos, Sara; Alarcón Morales, Karen Salua; Diercks, Tammo; Mato De La Paz, José María; Bernardo Seisdedos, Ganeko; Millet Aguilar-Galindo, Oscar
Congress name: Optimized Standard Operating Procedures for 31P-NMR Metabolomics on Tissular Extracts / Country: España / Web: https://euromar2024.org/ / Publication name: Optimized Standard Operating Procedures for 31P-NMR Metabolomics on Tissular Extracts / Start date: 2024/06/30 / End date: 2024/07/04
The Modulatory Effects of CHCHD10 protein in TDP-43's Liquid-Liquid Phase Separation Properties and Aggregation Dynamics
Alarcón Morales, Karen Salua; Martín Ramos, Sara; Pozo Fernandez, Sara; Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Congress name: The Modulatory Effects of CHCHD10 protein in TDP-43's Liquid-Liquid Phase Separation Properties and Aggregation Dynamics / Country: España / Web: https://www.biophysicssansebastian2024.com/ / Publication name: The Modulatory Effects of CHCHD10 protein in TDP-43's Liquid-Liquid Phase Separation Properties and Aggregation Dynamics / Start date: 2024/06/05 / End date: 2024/06/07
The Modulatory Effects of CHCHD10 protein on TDP-43's Aggregation Dynamics
Alarcón Morales, Karen Salua; Pozo Fernandez, Sara; Martín Ramos, Sara; Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Congress name: The Modulatory Effects of CHCHD10 protein on TDP-43's Aggregation Dynamics / Country: España / Web: https://annualmeeting.ciberned.es/ / Publication name: The Modulatory Effects of CHCHD10 protein on TDP-43's Aggregation Dynamics / Start date: 2024/04/10 / End date: 2024/04/12
De la ciencia básica al paciente: implicaciones de la proteostasis en enfermedades raras
Bernardo Seisdedos, Ganeko
Congress name: De la ciencia básica al paciente: implicaciones de la proteostasis en enfermedades raras / City: Alicante / Web: https://www.cnemcongress.com/ / Publication name: De la ciencia básica al paciente: implicaciones de la proteostasis en enfermedades raras / Start date: 2023/10/25 / End date: 2023/10/27
Liver metabolic landscape of the murine NASH models by quantitative 31P-NMR analysis of the phosphorome
Bernardo Seisdedos, Ganeko
Congress name: Liver metabolic landscape of the murine NASH models by quantitative 31P-NMR analysis of the phosphorome / Country: España / Publication name: Liver metabolic landscape of the murine NASH models by quantitative 31P-NMR analysis of the phosphorome / Start date: 2022/06/27 / End date: 2022/06/30
Metabolic landscape of the mouse liver by quantitative 31P-NMR analysis of the phosphorome
Bernardo Seisdedos, Ganeko
Congress name: Metabolic landscape of the mouse liver by quantitative 31P-NMR analysis of the phosphorome / City: Barig / Country: Italia / Publication name: Metabolic landscape of the mouse liver by quantitative 31P-NMR analysis of the phosphorome / Start date: 2021/10/04 / End date: 2021/10/08
Metabolic landscape of the mouse liver by quantitative 31P-NMR analysis of the phosphorome.
Bernardo Seisdedos, Ganeko
Congress name: Metabolic landscape of the mouse liver by quantitative 31P-NMR analysis of the phosphorome. / Country: España / Publication name: Metabolic landscape of the mouse liver by quantitative 31P-NMR analysis of the phosphorome. / Start date: 2020/12/07 / End date: 2020/12/08
NMR insights on the recognition mechanism of histo-blood group antigens by human galectin-1
Bernardo Seisdedos, Ganeko
Congress name: NMR insights on the recognition mechanism of histo-blood group antigens by human galectin-1 / Country: España / Publication name: NMR insights on the recognition mechanism of histo-blood group antigens by human galectin-1 / Start date: 2020/02/19 / End date: 2020/02/21
The effect of osmolytes in biomolecular stability as investigated by NMR spectroscopy. Lessons from halophilic proteins
Bernardo Seisdedos, Ganeko
Congress name: The effect of osmolytes in biomolecular stability as investigated by NMR spectroscopy. Lessons from halophilic proteins / City: San Diego / Country: Estados Unidos De America / Publication name: The effect of osmolytes in biomolecular stability as investigated by NMR spectroscopy. Lessons from halophilic proteins / Start date: 2019/12/06 / End date: 2019/12/09
Heme Biosynthetic Pathway Regulation Studied by NMR Spectroscopy and Computational Methods
Bernardo Seisdedos, Ganeko
Congress name: Heme Biosynthetic Pathway Regulation Studied by NMR Spectroscopy and Computational Methods / Country: Italia / Publication name: Heme Biosynthetic Pathway Regulation Studied by NMR Spectroscopy and Computational Methods / Start date: 2019/09/08 / End date: 2019/09/11
Structural basis and energy landscape for the Ca 2+ -gating and calmodulation of the Kv7.2 K + channel
Bernardo Seisdedos, Ganeko
Congress name: Structural basis and energy landscape for the Ca 2+ -gating and calmodulation of the Kv7.2 K + channel / City: Santiago de Compostela / Country: España / Publication name: Structural basis and energy landscape for the Ca 2+ -gating and calmodulation of the Kv7.2 K + channel / Start date: 2017/09/06 / End date: 2017/09/08
Heme group biosynthesis modulation by Porphobilinogen Deaminase inhibition
Bernardo Seisdedos, Ganeko
Congress name: Heme group biosynthesis modulation by Porphobilinogen Deaminase inhibition / City: Bordeaux, / Country: Francia / Publication name: Heme group biosynthesis modulation by Porphobilinogen Deaminase inhibition / Start date: 2017/06/25 / End date: 2017/06/28
Structural insides of Calmodulin/Kv7.2 channel complex: the calcium effect
Bernardo Seisdedos, Ganeko
Congress name: Structural insides of Calmodulin/Kv7.2 channel complex: the calcium effect / Country: España / Publication name: Structural insides of Calmodulin/Kv7.2 channel complex: the calcium effect / Start date: 2016/09/05 / End date: 2016/09/08
Structural insides of Calmodulin/K v 7.2 channel complex: The calcium effect
Bernardo Seisdedos, Ganeko
Congress name: Structural insides of Calmodulin/K v 7.2 channel complex: The calcium effect / Country: España / Publication name: Structural insides of Calmodulin/K v 7.2 channel complex: The calcium effect / Start date: 2016/06/28 / End date: 2024/11/27
Structural elucidation of Calmodulin bound to helices A and B of Kv7.2 channels. The calcium effect.
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Congress name: Structural elucidation of Calmodulin bound to helices A and B of Kv7.2 channels. The calcium effect. / Country: España / Publication name: Structural elucidation of Calmodulin bound to helices A and B of Kv7.2 channels. The calcium effect. / Start date: 2015/11/11 / End date: 2015/11/13
Structural characterization of calmodulin bound to the intracellular calmodulin binding domain of Kv7.2 channels by NMR
Millet Aguilar-Galindo, Oscar; Bernardo Seisdedos, Ganeko
Congress name: Structural characterization of calmodulin bound to the intracellular calmodulin binding domain of Kv7.2 channels by NMR / Country: España / Publication name: Structural characterization of calmodulin bound to the intracellular calmodulin binding domain of Kv7.2 channels by NMR / Start date: 2015/07/22 / End date: 2015/07/25
Calmodulin binding to a novel site in the AB module of Kv7.2 subunit regulates surface expression
Bernardo Seisdedos, Ganeko
Congress name: Calmodulin binding to a novel site in the AB module of Kv7.2 subunit regulates surface expression / City: Baltimore / Country: Estados Unidos De America / Publication name: Calmodulin binding to a novel site in the AB module of Kv7.2 subunit regulates surface expression / Start date: 2015/02/07 / End date: 2015/02/11
Characterization of the Kv7.2 potassium channel calmodulin binding site
Bernardo Seisdedos, Ganeko
Congress name: Characterization of the Kv7.2 potassium channel calmodulin binding site / Country: España / Publication name: Characterization of the Kv7.2 potassium channel calmodulin binding site / Start date: 2013/07/02 / End date: 2013/07/04
Sistema autónomo y no invasivo para toma de flujometrías sonoras fuera del entorno hospitalario
Arjona Aguilera, Laura; Bernardo Seisdedos, Ganeko; Díez Blanco, Luis Enrique; Egaña Aretxabaleta, Aimar; Onieva Caracuel, Enrique
Abstract: E PROCESS MED S.L. / Start date: 2023/06/01 / End date: 2023/12/31
Investigadora Principal del equipo DeustoMED del Departamento de Medicina de la Facultad de Ciencias de la Salud de la Universidad de Deusto.
Las Hayas Rodríguez, Carlota; GARCIA, RODRIGO DAMIAN; Solís Mencía, Cristian; CAMARÓN ALONSO, GAIZKA; BERNARDO SEISDEDOS, GANEKO; Bringas Grande, Arantza; Alvarez-Hornia Pérez, Eduardo; Mas Bilbao, Naia; García Gutiérrez, Susana; Armentia Bardeci, Jesús María; GUTIERREZ AGUIRREGABIRIA, ANE; Romero Yesa, Susana; Cuesta Zigorraga, Amaia
Merit type: Mérito De Investigación / Start date: 2023/12/22 / End date: 2024/11/27
Premio José Tormo de la Sociedad Española de Bioquímica y Biología Molecular
BERNARDO SEISDEDOS, GANEKO
Merit type: Mérito De Investigación / Start date: 2018/04/18 / End date: 2024/11/27